About 1 result found for searched term "AAPK-25 " (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29436 | AAPK-25 | Aurora Kinase |
| AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. AAPK-25 targets Aurora-A, -B, and -C with Kd values ranging from 23-289 nM, as well as PLK-1, -2, and -3 with Kd values ranging from 55-456 nM. | ||
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